Chronic low-grade inflammation, also called inflammaging, and glycation are directly associated with metabolic disorders and age-related obesity.
Concordant studies show that rosmarinic acid has inhibitory effects on inflammation and excessive lipid accumulation (1 and 2).
These results suggest that rosmarinic acid, whose deglycating effect has been demonstrated in vitro, may be a promising product for the treatment of age-related obesity.
© Age Breaker 05 2021[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]
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(1): L. Vasileva et al. Rosmarinic acid attenuates obesity and obesity-related inflammation in human adipocytes. Food Chem Toxicol. 2021. Mar;149:112002. doi: 10.1016/j.fct.2021.112002
(2): Y. Rui. Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-α secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes. Food Nutr Res. 2017 Jun 7;61(1):1330096. doi: 10.1080/16546628.2017.1330096.