A high level of glycation, a marker of biological aging, would increase the risk of transmission of the metabolic syndrome between mother and child, leading to an uncontrollable increase in cases of early aging.
A study conducted in Bordeaux among pregnant women shows that a high glycation rate is associated with the macrosomia of their children. Of 343 pregnant women with a metabolic syndrome or gestational diabetes, 11% of them, with the highest glycation levels, gave birth to a macrosomic child (birth weight over 4 kg).
Their average glycation rate was equivalent to a 50-year-old, about 15 years older than their chronological age…
A detailed analysis of the results shows that their average glycation rate was equivalent to a 50-year-old, about 15 years older than their chronological age (33 years on average).
The mechanism of transmission is not known but likely involves epigenetic.
These results are particularly worrying. As the metabolic syndrome has reached epidemic levels in many countries among reproductive age women, the birth rate of overweight children will increase mechanically. Finally, knowing that a high birth weight is a risk factor for the occurrence of the metabolic syndrome throughout life, the epidemic of metabolic syndrome will reach more or less long term uncontrollable levels.
To be continued…
© AGE BREAKER, update 05 2020[AGE BREAKER METABOLISM, patented nutritional supplement, based on rosmarinic acid, recognized by aging specialists around the world for its properties to reverse the effects of glycation.] [Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.]
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(1): N. Foussard et Al. Skin Autofluorescence of Pregnant Women With Diabetes Predicts the Macrosomia of their Children. Hôpital haut Lévêque Bordeaux, France. American Diabetes Association, 05 2019.
Photo ; Toscani & Rosalind Breen