GLYCATION GLYCATION & METABOLISM

Aging and metabolism: from intermittent fasting to circadian intermittent fasting.

Intermittent fasting aligned with the circadian rhythm, a formidable weapon in the fight against aging and age-related diseases.

Intermittent fasting consists in grouping all meals over 8 hours in a 24-hour cycle, for example by skipping breakfast.

The benefits: after 12 hours without food, insulin levels drop mechanically, resulting in a reduction in body fat and sugars stored in the body (1).

New research suggests that not all approaches to intermittent fasting are the same (2). For example, intermittent fasting in which meals are concentrated over an 8-hour period starting early in the day (e.g. 7 a.m. – 3 p.m.) has better results than intermittent fasting in which the meal period is later (e.g. 12 p.m. – 8 p.m.). These results are linked to the influence of circadian rhythms, in other words the biological clock. We then speak of eTRF (early Time-Restricted Feeding), or simply circadian intermittent fasting.

The results are spectacular: improvement in all parameters of the metabolic syndrome, starting with a fairly rapid drop in weight, a reduction in heart rate, blood pressure…

Consequences: circadian intermittent fasting prevents many age-related diseases: diabetes, cardiovascular disease, certain forms of cancer, neurodegenerative diseases. Circadian intermittent fasting also increases life expectancy.

© AGE Breaker, updated 10 2023

[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.]
[AGE Breaker, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]

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(1) : R. de Cabo et Al. Effects of Intermittent Fasting on Health, Aging, and Disease. N Engl J Med 2019 381:2541-2551. DOI: 10.1056/NEJMra1905136

(2) : Jamshed H et Al. Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans. Nutrients 2019, 11(6), 1234; Doi.org/10.3390/nu11061234