GLYCATION GLYCATION & METABOLISM

Abdominal overweight, an early sign of aging!

Sugar consumption and glycation are at the heart of a cascade of interactions that lead to metabolic disturbances and accelerated aging.

Junk food and particularly over-consumption of sugars are responsible for excess fat production (1). This excess fat is stored in the abdominal visceral area and not in the subcutaneous adipose tissue, the physiological site of fat storage.

Excess visceral fat is at the root of metabolic abnormalities, aggravated by glycation, itself a direct consequence of excess sugars (2), all leading to accelerated aging.

This is why a protruding belly is a major predictive factor of aging.

Numerous studies show that regular consumption of sugar-sweetened beverages is associated with an increase in visceral adipose tissue (3). Some of these studies show that these mechanisms begin in adolescence or even childhood! (4).

This is how even before the appearance of loss of functionality and visible signs of aging, the spiral of biological aging is set in motion – and increasingly so in childhood!

Strict diet and lifestyle help prevent abdominal overweight from developing into metabolic syndrome.

Reducing the consumption of sugars, and in particular sugar-sweetened beverages, is a crucial step in the fight against aging and the prevention of age-related diseases.

© AGE Breaker, updated 09 2023

[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE Breaker, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]

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1 J.-J. Di Nicolantonio et Al. Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity. Progress in Cardiovascular Diseases. Volume 61, Issue 1, May–June 2018.

https://doi.org/10.1016/j.pcad.2017.12.001

2 D. Sergi et Al. The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction. Molecular Nutrition and Food Research, April 2020.

https://doi.org/10.1002/mnfr.201900934

3 Jiantao Ma et Al. Sugar-Sweetened Beverage Consumption Is Associated With Change of Visceral Adipose Tissue Over 6 Years of Follow-Up. Circulation Volume 133, Issue 4, 26 January 2016.

https://doi.org/10.1161/CIRCULATIONAHA.115.018704

4 V. Calcaterra et Al. Sugar-Sweetened Beverages and Metabolic Risk in Children and Adolescents with Obesity: A Narrative Review. Nutrients 2023, 15(3),702;

https://doi.org/10.3390/nu15030702