GLYCATION & METABOLISM

Metabolic age, a new indicator of aging?

Metabolic age, an easily measurable component of biological age, appears to be a good predictor of accelerated aging.

Unlike chronological age, a simple measure of time, biological age reflects the functionality of the organism. It integrates numerous factors such as genetics, behavior, etc. It should make it possible to predict aging.

The search for reliable indicators of biological age is evolving rapidly, thanks to advances in molecular biology. They combine different types of predictors that are often difficult to evaluate, such as epigenetic clocks, telomeres, etc. (1).

While waiting for a biological age standard more reliable, metabolic age, a simple component of the latter, makes it easy to approach the concept of aging prediction.

To function, the body consumes energy in the form of calories. The amount of calories required for the body to function at rest for 24 hours is called the basal metabolic rate.

Metabolic age is determined by comparing this basal metabolic rate with the average basal metabolic rate of people of the same chronological age.

A metabolic age higher than chronological age appears to be a relevant indicator of risk for metabolic syndrome and accelerated aging (2).

Several algorithms are available for measuring metabolic age.

Simpler, using electrical impedance analysis techniques, devices such as household scales provide a rapid, accurate and traceable estimate of metabolic age.

Increasingly popular in sports medicine, the use of these impedance meters can easily form the first step in an anti-aging medical check-up.

© AGE Breaker, updated 11 2023

[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE Breaker, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]

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(1) : J. Jylhävä et Al. Biological Age Predictors, eBioMedicine 2017-07

doi.org/10.1016/j.ebiom.2017.03.046

(2) : R. Elguezabal-Rodelo et Al. Metabolic age correlates better than chronological age with waist-to-height ratio, a cardiovascular risk index. Medicina Clinica, Volume 157, Issue 9, 12 November 2021, P 409-417. doi.org/10.1016/j.medcli.2020.07.026