High levels of glycation are significantly associated with higher risks of heart failure.
Heart failure, the inability of the heart to ensure sufficient blood flow for the body’s needs, increases rapidly with age, especially from the age of 70.
It has a strong impact on quality of life and then worsens over time, apparently irreversibly, leading to a high mortality rate, around 50% 5 years after the onset of symptoms.
A veritable vicious circle, heart failure worsens when the heart tries to adapt.
Based on data from the Rotterdam study, researchers provide evidence that high levels of glycation (reactions between body proteins and sugar residues that accumulate in the human body) are significantly associated with an elevated risk of heart failure (1). Interestingly, these associations are independent of diabetes status and are present in people with and without diabetes.
These results confirm the interest of studying the effects of products fighting against glycation and particularly AGEs Cross Links Breaker in heart failure.
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[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]More on www.agebreaker.com
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(1): B. Arshi et Al. Advanced glycation end-products, cardiac function and heart failure in the general population: The Rotterdam Study. Diabetologia volume 66, pages472–481 (2023). https://doi.org/10.1007/s00125-022-05821-3