PROCEDURES OF PLASTIC SURGERY AND AESTHETIC MEDICINE : how to avoid the pitfall of glycated elastin ?

You can always stretch, tighten, lift, inject or boost the skin … But restore skin elasticity is possible only by taking the problem at its source: glycation.

Elastin gives the dermis fibers the elasticity that allows the skin to regain its original position after being stretched. Elastic fibers are synthesized in the peri-natal period and in childhood. In adulthood the renewal of elastin is almost zero except in cases of healing where the synthesis of elastin is reactivated but less effectively.

Elastin, one of the most resistant proteins in the body, is difficult to degrade. Its weak point is its low turnover (half-life estimated at more than 70 years) which exposes it to the damage of the glycation. Years after years the AGEs (advanced glycation products resulting from the fixing of sugars on proteins), create cross links which definitively reduce the elasticity of elastin.

The recent discovery of the deglycating properties of certain molecules reverses this situation. Thus, taking Age Breaker, the first deglycating product available on the market, has restored 16.9% of skin elasticity in one month (corresponding to 10 years of cutaneous elasticity gained) in patients aged 58 years on average (1).

So, before any plastic or aesthetic procedure, especially on mature skin (over 45 / 50 years), the prescription of a deglycating cure, 2 to 4 weeks before the intervention, is a good practice to adopt.