Not respecting the biological rhythms of food and sleep induces poor glucose metabolism.
Our body has its own biological clocks based on a circadian rhythm – about 24 hours.
These biological rhythms, specific to each organ, allow the body to adapt to predictable daily changes such as the alternation of day/night or food/fasting.
The disruption of certain rhythms can have serious health consequences.
Thus, the circadian regulation of glucose metabolism – a key factor in age-related diseases – is tuned to tolerate glucose better in the morning than in the afternoon or evening. The magnitude of circadian variation in glucose tolerance is surprisingly large: the same dose of glucose, normally tolerated in the morning, may have pathological metabolic consequences in the evening (1).
Circadian misalignment, induced by a high glycemic index diet in the evening, increases the risk of developing metabolic diseases such as diabetes and its complications as well as accelerated aging
Worse, the circadian misalignment induced by inappropriate light exposure at night also affects glucose metabolism and metabolic health.
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(1): E. Poggiogalle et al. Circadian regulation of glucose, lipid, and energy metabolism in humans. Metabolism 2018 Jul; 84:11-27. DOI: 10.1016/j.metabol.2017.11.017
