Over-consumption of sugar is thought to accelerate age-related loss of bone density through glycation.
The decline in bone density begins around the age of 30. It progresses more rapidly in women than in men. Its effects on bone fragility lead to an increase in the frequency of fractures, deformities and chronic pain, and ultimately to a reduction in height of a few centimetres per decade, and even up to 10 cm after the age of 60!
Researchers have highlighted the critical impact of high glucose consumption on the composition of the extracellular matrix of bone, leading to a weakening of bone quality. This is due to glycation, the binding of sugars to the body’s proteins, which alters collagen cross-linking and reduces the integrity of the bone matrix (1).
Given the time lag between the onset of bone density loss, at around age 30, and its effects on aging decades later (at around age 50 in women, 60 in men), it is important to introduce appropriate lifestyle and dietary measures very early on (supplements, physical exercise), and in particular to drastically limit sugar consumption!
© AGE Breaker 01 2025
[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]More on www.agebreaker.com
#agebreaker #glycation #antiaging #longevitymedicine #preventivemedicine #preventivehealth #skinaging #4pmedicine #advancedglycationendproducts
(1): ARAÚJO, Rita, PÁSCOA, Ricardo NMJ, BERNARDINO, Raquel, et al. Impact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model. Cells, 2025, vol. 14, no 2, p. 130.
https://doi.org/10.3390/cells14020130
