GLYCATION

Sleep deprivation, an accelerator of aging?

Glycation may explain why sleep deprivation increases cardiovascular risks.

Sleep duration varies according to age, culture and lifestyle. Numerous studies show a steady decline in this sleep duration, particularly in the Western world, where average sleep time has fallen by 1.5 hours in 50 years.

Sleep is recognized as a key factor in good health. Thus, validating the association between sleep deprivation and cardiovascular risk, the American Heart Association has included sleep as a component of the cardiovascular health score. The causal relationship has yet to be established.

By analyzing associations between sleep duration and biomarkers of cardiovascular risk, researchers have shown a correlation between sleep duration and glycation (1). Glycation increased significantly when sleep duration fell below 6 hours per night.

These results confirm that insufficient sleep increases cardiovascular risk.

Although this remains to be proven, it is reasonable to assume that sleep deprivation is a cause of increased glycation. Glycation, resulting from over-consumption of sugar, is one of the main factors in aging. Sleep deprivation would therefore be an accelerator of aging.

To be continued…

© AGE Breaker 09 2024

[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]

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(1) : MARTÍNEZ-GARCÍA, Irene, SAZ-LARA, Alicia, CAVERO-REDONDO, Iván, et al. Association between sleep duration and cardiovascular risk: the EVasCu cross-sectional study. Frontiers in Physiology, 2024, vol. 15, p. 1430821.

https://doi.org/10.3389/fphys.2024.1430821