The accumulation of heavy metals promotes glycation, which itself would act on the toxicity of heavy metals.
Trace metal elements (or TMEs), the new name for heavy metals, are used in a wide range of industrial applications, leading to their release into the environment in ever-increasing, persistent quantities.
Some of these metals are essential to health when used in limited quantities (iron, zinc, copper, etc.).
Non-essential metals, on the other hand, are toxic even in low concentrations (mercury, lead, etc.).
Heavy metals enter the body in various ways: water, food, inhalation… Their accumulation can seriously affect all organs and vital functions.
Several studies show that exposure to many heavy metals, particularly toxic heavy metals (cadmium, mercury, lead…) promotes glycation, a major factor in aging (1). Conversely, certain essential metals such as zinc and selenium have anti-glycation effects.
The same studies show that glycation itself has an effect on the toxicity of heavy metals. These results suggest that combating glycation could be seen as a potential strategy for reducing metal toxicity.
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[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]More on www.agebreaker.com
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(1) : SKALNY, Anatoly V., ASCHNER, Michael, SANTAMARIA, Abel, et al. The Differential Role of Toxic and Essential Metals in Formation and Toxicity of Advanced Glycation End-Products. Toxicology of Essential and Xenobiotic Metals, 2024, p. 160-198.
https://doi.org/10.1201/9781003300496