Aging is not linear; its mechanisms are in place many years before the appearance of its first signs.
Aging begins when tissues and organs begin to lose function as a result of cell degradation. Some organs, such as the skin, see certain functions begin to decline, while others, such as the brain, are still developing.
However, there is a consensus that aging begins between the ages of 25 and 35.
Based on the evolution of 5 parameters (metabolism, bone structure, muscles, memory, sleep) in 4,263 people aged between 18 and 95, researchers have shown that aging is not linear, but progresses in 3 stages: 30, 60 and 80 (1).
The mechanisms of aging are in place for a long time, sometimes decades, before the first signs of aging appear.
The average age of the first consultation with anti-aging medicine is 45 – 50, i.e. the age of the established signs of aging.
Based on experimental studies showing that anti-aging treatments, such as Metformin, are more beneficial if started early in life (2), some specialists are leaning towards early management of aging, as early as 25 – 30 years old, starting with a complete check-up.
© AGE Breaker, updated 07 2024
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(1) : T. LEHALLIER, Benoit, GATE, David, SCHAUM, Nicholas, et al. Undulating changes in human plasma proteome profiles across the lifespan are linked to disease: Biomarkers (non‐neuroimaging): Novel biomarkers. Alzheimer’s & Dementia, 2020, vol. 16, p. e043868. https://doi.org/10.1002/alz.043868
(2) : ANISIMOV, Vladimir N., BERSTEIN, Lev M., POPOVICH, Irina G., et al. If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. Aging (Albany NY), 2011, vol. 3, no 2, p. 148. doi: 10.18632/aging.100273
