Paradox: progress in knowledge does not stop the decline in life expectancy.
Decoding the human genome, understanding the biological mechanisms of aging such as glycation, stem cells or telomeres, using artificial intelligence to develop new classes of drugs such as senolytics…
Scientific and technological progress in the field of aging has been considerable since the early 2000s. They suggest an imminent revolution in longevity.
For the past decade, life expectancy in developed countries has been stagnating or even declining. Life expectancy in good health is not increasing either. Moreover, specialists agree that COVID does not explain all of the decline in life expectancy observed in 2020 and 2021.
One explanation is that while scientific discoveries have not yet translated into medical advances, lifestyles are slowly changing. Junk food, toxic substances (sugar, tobacco, alcohol, drugs), chronic stress, staggered hours, sedentarily lifestyle… continue to produce their deleterious effects.
Moreover, due to epigenetic mechanisms, we are moving towards 2 types of population whose life expectancy diverges: the “losers” (stress, obesity, immune weakness…) whose life expectancy is reduced, as for example in the United States, and the “winners” (favorable genetic profile, life discipline…) whose life expectancy continues to improve, as for example in Japan (1).
[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]© AGE Breaker 04 2023
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(1) : https://www.worldometers.info/demographics/life-expectancy/
