Longevity medicine: between hope and skepticism.
The science of aging is advancing rapidly. In ten years, scientific publications devoted to longevity have doubled.
Epigenetic clocks, glycation reactions, the role of telomerase, and the potential of stem cells… understanding the mechanisms of aging raises immense hopes: living longer and in better health!
This dynamic is fueling growing demand from an enthusiastic public: drugs, dietary supplements, behavioral changes, and even biotechnological solutions bordering on transhumanism.
But as hope grows, so does doubt. Many suspect excessive promises and hype. Sometimes unrealistic expectations interfere with scientific debate and risk diverting attention from serious research, thereby slowing its progress.
Longevity medicine: why so much skepticism?
A recent article (1) highlights the persistent gap between public expectations and scientific realities when it comes to longevity.
Three main causes stand out:
- Excessive promises: the credibility of longevity science has been undermined by the massive marketing of supplements and therapies with vague, general claims such as “anti-aging,” which have led to confusion and mistrust.
- Insufficient scientific validation: regulatory and intellectual property constraints, weak pharmacological and clinical data, difficulties in transposition… these are all obstacles that prevent a clear consensus on the real benefits.
- Difficult communication: popularizing complex scientific data to a general public accustomed to short, immediate messages is a difficult task, made even more challenging by the rapid consumption patterns imposed by social media.
Towards credible longevity medicine:
In the absence of consensus on the regulation of longevity-related products and reliable markers of aging, public confidence will depend on good practices and self-discipline among industry players. Three priorities are essential:
- Ethics: safety first, with complete transparency on benefits and risks.
- Rigour: basing every advance on solid pharmacology, clinical trials, and strict monitoring.
- Education: training healthcare professionals, publishing in recognized journals, and engaging in open debate with the scientific community.
Healthy longevity is not a mirage. It requires patience, rigor, and honesty. The challenge is not only scientific: it is also ethical and cultural.
© AGE Breaker 09 2025
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- Yu, D., Zeng, X., Barzilai, D. et al.Bridging expectations and science: a roadmap for the future of longevity interventions. Biogerontology 26, 138 (2025). https://doi.org/10.1007/s10522-025-10278-z