The mechanisms of glycation are present many years before the appearance of clinical signs of skin aging. The discovery of deglycating molecules makes it possible to take care of this aging factor with consequences known to be difficult to reverse.
In a healthy patient, the endogenous increase of AGEs (Advanced Glycation Endproducts) in skin collagen is very slow and linear throughout life. The growth rate of AGEs is estimated at around 0.5% per year between 20 and 80 years (1); the clinical consequences of the accumulation of AGEs are not perceptible before long. Thus, skin elasticity does not begin to decrease significantly until around 45/50 years (2).
At the same time, glycation is accelerated by external factors, such as overconsumption of sugar, pollution and above all, for the skin, irradiation (UVs, laser, etc.). In patients with risk behavior, signs of skin aging related to glycation can be seen from the age of 35/40 years.
Once the signs of aging have been established, only taking a deglycating product, such as Age Breaker, will reverse some clinical signs of skin aging.
To take in cures of some months, from 40 years for people at risk and 50 years for everyone.
@ AGE BREAKER, update 12 2020
(1): JA Duen and Al. Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen. Department of Chemistry. University of South Carolina, Columbia 29208. Biochemistry 1991 Feb 5; 30(5):1205-10.
(2): M. Ichihashi and Al. Glycation Stress and Photo-Aging in Skin. Anti aging Medical Research Center and Glycation Stress Research Center, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan. 2011.[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER SKIN HEALTH, patented nutritional supplements, based on rosmarinic acid, recognized around the world by aging specialists for their properties to reverse the effects of glycation.]
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