GLYCATION: an excellent marker of aging, how to apprehend it in a doctor’s office

The complexity of the glycation assessment and the diversity of its effects confirm the importance of a participatory consultation in anti-aging medicine.

Glycation, a biochemical reaction, appears more and more as the major factor in aging, knowledge of which is constantly improving.

Its complexity and the heterogeneity of its consequences make it a difficult area to understand for physicians and patients.

About ten methods are used to assess the degree of glycation, but those which are simple are imprecise (measurement of skin autofluorescence for example), others more relevant are complex to implement, very expensive and often to date. not accessible to the practitioner of anti-aging medicine (Elisa, Western blotting for example) (1).

Conveniently, the clinical consequences of glycation, which are moreover often multifactorial, are very diverse. The coexistence of these signs (metabolic syndrome, musculoskeletal disorders, pigment spots, etc.) with a family history (diabetes, cardiovascular and neurodegenerative diseases) and risky behaviors (junk food, stressful life, etc.) will easily alert the doctor to a level of glycation during a first anti-aging consultation.

Glycation-related aging scoring can thus become as essential indicators as blood pressure, BMI or HOMA in controlling aging.

© AGE BREAKER 02 2021

[AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.]
[Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.]

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(1) : Anna Perrone et Al. Advanced Glycation End Products (AGEs): Biochemistry, Signaling, Analytical Methods, and Epigenetic Effects. Oxidative medicine and cellular longevity. Published online 2020 Mar 18. doi: 10.1155/2020/3818196